Mega MSM bottle
Clinically proven Mega MSM supplement bottle with promotional text against a blurred outdoor background
Two white capsules with Joint Support Complex on a blue background
Man and woman sitting at a table with a bottle of US Clinics Mega MSM and a glass of water, with text about healthy joints.
Woman holding an apple with text about added vitamin C and MSM benefits.
Mega MSM supplement bottle with capsules and a glass on a blue background
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Hand holding a bottle of U.S. Doctors' Clinical Mega MSM supplement with a blue background and text about 'Manufactured in the USA'.
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Mega MSM bottle 3 pack
Mega MSM bottle 6 pack
(31 reviews)

Mega MSM

Sale price$26.99
Size: 60 Servings, 2 Capsules per serving

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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Product Facts

    • COMFORTABLE MOVEMENT SUPPORT: Methylsulfonylmethane, or MSM, is organic, bioactive sulfur that is found in healthy connective tissue. MSM can also help support comfortable movement.*
    • BEYOND COLLAGEN: MSM supports the body’s production of collagen. The addition of collagen from poultry in this MSM supplement helps support the body’s natural collagen stores for healthy ligaments and tendons.*
    • CLINICALLY-PROVEN, DOCTOR FORMULATED: This MSM supplement is doctor-formulated with intentional ingredients to nourish cartilage and provide reliable support joint health*
    • UNIQUE HERBAL BLEND: Used in traditional practice, neem promotes tissue health.* Corydalis provides support and promotes balanced hormone levels to help encourage the maintenance of wellness during times of stress.*
    • PREMIUM INGREDIENTS: U.S. Doctors’ Clinical Mega MSM capsules contain high-quality ingredients and are manufactured in the USA in a cGMP-certified facility with third-party quality control audits. They are backed by the Advisory Board of Doctors.

Doctor-Backed Supplements You Can Trust

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Real Customer Support

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7 Clinically Tested Formulas

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USA Manufactured

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Third-Party Tested

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Gluten-Free

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Doctor-Backed Supplements

For Joint Health

U.S. Doctors’ Clinical Mega MSM is a clinically tested supplement formulated to help support comfortable movement and overall joint function.* This advanced formula features Methylsulfonylmethane (MSM), a natural source of bioactive sulfur found in healthy connective tissue, combined with key ingredients selected to nourish and support joint comfort.*

Woman in blue outfit with U.S. Doctors' Clinical Mega MSM product on red background

Doctor-Recommended MegaMSM

MegaMSM is a doctor-recommended and clinically tested joint support supplement from U.S. Doctors' Clinical.

Woman in blue outfit with U.S. Doctors' Clinical Mega MSM product on red background

Doctor-Recommended MegaMSM

MegaMSM is a doctor-recommended and clinically tested joint support supplement from U.S. Doctors' Clinical.

Self-Reported Joint Health Improvement*

In the double-blind placebo-controlled clinical study, those who took Mega MSM reported significant joint health improvements compared to a placebo.*

Bar chart comparing self-reported joint health improvement between MegaMSM and placebo groups.
Bar chart comparing self-reported joint health improvement between MegaMSM and placebo groups.

Self-Reported Joint Health Improvement*

In the double-blind placebo-controlled clinical study, those who took Mega MSM reported significant joint health improvements compared to a placebo.*

Table showing joint examination improvement percentages for MegaMSM and placebo.

Joint Exam Improvement*

In the clinical study, those who took Mega MSM experienced joint comfort, movement and flexibility improvements compared to placebo.*

Table showing joint examination improvement percentages for MegaMSM and placebo.

Joint Exam Improvement*

In the clinical study, those who took Mega MSM experienced joint comfort, movement and flexibility improvements compared to placebo.*

Quality of Live Improvement*

In the clinical study, those who took MegaMSM reported significant quality of life improvements such as physical function, bodily comfort, social function, and mental composite score, compared to placebo.*

Table showing quality of life improvement measures with 'YES' for each category on a white background.
Table showing quality of life improvement measures with 'YES' for each category on a white background.

Quality of Live Improvement*

In the clinical study, those who took MegaMSM reported significant quality of life improvements such as physical function, bodily comfort, social function, and mental composite score, compared to placebo.*

Capsule with 'Powerful Ingredients' label on a red background

Powerful Ingredients for Joint Support

Previously known as MSM Advanced, Mega MSM contains 1200 mg of MSM per serving, along with collagen and vitamin C to support joint collagen. This formula also delivers neem, a leaf that has been used in Ayurvedic practice for a wide range of health benefits. We added corydalis extract, which comes from Chinese medicine, to provide further support for limbs and nerve function.*

Capsule with 'Powerful Ingredients' label on a red background

Powerful Ingredients for Joint Support

Previously known as MSM Advanced, Mega MSM contains 1200 mg of MSM per serving, along with collagen and vitamin C to support joint collagen. This formula also delivers neem, a leaf that has been used in Ayurvedic practice for a wide range of health benefits. We added corydalis extract, which comes from Chinese medicine, to provide further support for limbs and nerve function.*

Clinically Tested, Doctor-Recommended

Mega MSM is manufactured in the United States in our cGMP (current Good Manufacturing Practices) certified facility that is regularly audited for quality control by independent organizations like NPA, NSF, and UL. 

Clinically Tested, Doctor-Recommended

Mega MSM is manufactured in the United States in our cGMP (current Good Manufacturing Practices) certified facility that is regularly audited for quality control by independent organizations like NPA, NSF, and UL. 

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Customer Reviews
(31 reviews)
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Price
Sale price$26.99
Sale price$29.99
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Sale price$34.99
Key Benefit
Joint Support*
Joint Support*
Joint Support*
Joint Support*
Active Ingredients
MSM, Collagen, Neem, Corydalis extract
AR7 Joint Complex: Collagen, CMO, Lipase, MSM, Tumeric, Bromelain, Vitamin C
AR7 Joint Complex: Collagen, CMO, Lipase, MSM, Tumeric, Bromelain, Vitamin C
AR7 Joint Complex: Collagen, CMO, Lipase, MSM, Tumeric, Bromelain, Vitamin C
Additional Ingredients
Vitamin C
X
Hyaluronic Acid 100 mg
Hyaluronic Acid 10 mg
Doctor Recommended
Clinically Tested

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4.9
Rated 4.9 out of 5 stars
Based on 31 reviews
Total 5 star reviews: 28 Total 4 star reviews: 2 Total 3 star reviews: 1 Total 2 star reviews: 0 Total 1 star reviews: 0
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31 reviews
  • JN
    Jaunita N.
    Verified Buyer
    1 week ago
    Rated 5 out of 5 stars
    Msm

    Great stuff

    Was this helpful?
  • TG
    Tina G.
    Verified Buyer
    3 months ago
    Rated 5 out of 5 stars
    Mega is the best!

    I’ve been using this for years. Works great for my arthritis in my knees. Very noticeable if for some reason I stop taking it.

    Was this helpful?
  • RA
    Robert A.
    Verified Buyer
    9 months ago
    Rated 5 out of 5 stars
    Order satisfaction

    I ordered three bottles of MEGA MSM and received them promptly.

    Was this helpful?
  • CC
    Cheryl C.
    Verified Buyer
    1 year ago
    Rated 5 out of 5 stars
    Mega MSM

    I’ve been using this for years through Gera Vita and before. I’m so glad us doctors Carrie’s this product. Works for me and my husband loved it too.

    Was this helpful?
  • JK
    Jeff K.
    Verified Buyer
    1 year ago
    Rated 5 out of 5 stars
    Great

    This saved my knee from an operation. I recommend it to everyone who wants healthy joints. Excellent product!

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