Valerian (Valeriana Officinalis)
Has been researched in over 200 pharmacological studies published in scientific literature in Europe over the last 30 years. Six controlled clinical trials in Europe showed that Valerian was particularly effective for sleep problems as follows: Valerian shortened the time to fall asleep, prolonged sleep time, increased deep sleep stages, increased dreaming, reduced nighttime awakenings, and improved the quality of sleep in both normal sleepers and nsomniacs.
Melatonin (N-Acetyl-5-Methoxytryptamine)
Is produced by the pineal gland, located behind the third ventricle of the brain. Studies have shown that melatonin increased sleep onset latency in people with primary sleep disorders, melatonin increased the efficiency of normal sleepers, and melatonin decreased sleep onset latency in people with delayed sleep phase syndrome and people with insomnia.
Calcium
Is essential for normal sleep. In one published study in the European Neurology Journal, researchers found that calcium levels in the body are higher during some of the deepest levels of sleep, such as REM sleep. This study concluded that disturbances in sleep, especially the absence of deep REM sleep or disturbed REM sleep, are related to calcium deficiency. Restoration to the normal course of sleep was achieved by the normalization of blood calcium levels.
Magnesium
Deficiency results in chronic insomnia. This was proven in a study done by James Penland at the Human Nutrition Research Center in North Dakota, titled “Effects of Trace Element Nutrition on Sleep Patterns in Adult Women.” The study noted that it was important to have a balanced ratio of calcium and magnesium in addition to taking them together for best results.
Oats Extract (Avena Sativa)
Has historical evidence as a sleep aid because it contains many beneficial minerals such as calcium and magnesium. Historic remedies made from oats were traditionally used as an herbal nerve tonic. This tonic was given to patients with problems like depression and mental debility as well as nervous exhaustion.